Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. This article has been cited by other articles in PMC. Abstract Background Poor treatment adherence is common among patients with multiple sclerosis MS.
Multiple sclerosis signs and symptoms Main symptoms of multiple sclerosis A person with MS can have almost any neurological symptom or sign, with autonomicvisual, motor, and sensory A survey of multiple sclerosis being the most common.
While there are a number of environmental risk factors and although some are partly modifiable, further research is needed to determine whether their elimination can prevent MS. If migration takes place after age 15, however, the person retains the risk of their home country. Changes in this area increase the probability of getting MS.
MS is not considered a hereditary disease; however, a number of genetic variations have been shown to increase the risk. The hygiene hypothesis proposes that exposure to certain infectious agents early in life is protective, the disease is a response to a late encounter with such agents.
Only in a few cases and after many years does it cause demyelination. Individuals having never been infected by the Epstein—Barr virus are at a reduced risk of getting MS, whereas those infected as young adults are at a greater risk than those having had it at a younger age. This has led to the theory that uric acid is protective, although its exact importance remains unknown.
These features interact in a complex and not yet fully understood manner to produce the breakdown of nerve tissue and in turn the signs and symptoms of the disease.
These lesions most commonly affect the white matter in the optic nervebrain stembasal gangliaand spinal cordor white matter tracts close to the lateral ventricles.
The peripheral nervous system is rarely involved.
|Multiple sclerosis - Wikipedia||MNKa leading global specialty pharmaceutical company, today announced results from two company-sponsored surveys — the Multiple Sclerosis in America Survey Poster P and a national patient survey conducted by Harris Poll Poster P — that suggest patient-reported multiple sclerosis MS relapse rates may be higher than often thought.|
|Introduction||Question - Required - I am 18 years of age or older.|
|Survey of Symptoms and Quality of Life | Multiple Sclerosis UW Rehabilitation Research||Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.|
|Yahoo Finance's Morning Brief||A survey, summarizing the views of 2, multiple sclerosis MS patients, showed how people manage their disease in real life — and the results offer some surprising insights that might provide clues for future treatment development and optimization.|
When the myelin is lost, a neuron can no longer effectively conduct electrical signals. The T cells recognize myelin as foreign and attack it, explaining why these cells are also called "autoreactive lymphocytes".
A further breakdown of the blood-brain barrier, in turn, causes a number of other damaging effects such as swellingactivation of macrophagesand more activation of cytokines and other destructive proteins.
These factors could lead to or enhance the loss of myelin, or they may cause the axon to break down completely. It may become permeable to these types of cells secondary to an infection by a virus or bacteria.
After it repairs itself, typically once the infection has cleared, T cells may remain trapped inside the brain. The most commonly used diagnostic tools are neuroimaginganalysis of cerebrospinal fluid and evoked potentials.
Magnetic resonance imaging of the brain and spine may show areas of demyelination lesions or plaques. Gadolinium can be administered intravenously as a contrast agent to highlight active plaques and, by elimination, demonstrate the existence of historical lesions not associated with symptoms at the moment of the evaluation.
These brain responses can be examined using visual - and sensory- evoked potentials. Phenotypes use the past course of the disease in an attempt to predict the future course. They are important not only for prognosis but also for treatment decisions.
In CIS, a person has an attack suggestive of demyelination, but does not fulfill the criteria for multiple sclerosis. It is similar to the age that secondary progressive usually begins in relapsing-remitting MS, around 40 years of age.
There is debate on whether they are MS variants or different diseases. Management of multiple sclerosis Although there is no known cure for multiple sclerosis, several therapies have proven helpful.
The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. Starting medications is generally recommended in people after the first attack when more than two lesions are seen on MRI.
Alternative treatments are pursued by some people, despite the shortage of supporting evidence. Acute attacks During symptomatic attacks, administration of high doses of intravenous corticosteroidssuch as methylprednisoloneis the usual therapy,  with oral corticosteroids seeming to have a similar efficacy and safety profile.
They are interferon beta-1ainterferon beta-1bglatiramer acetatemitoxantronenatalizumabfingolimodteriflunomide  dimethyl fumarate alemtuzumab  and ocrelizumab. The disease-modifying treatments have several adverse effects.People who are over 18 years old and have MS are invited to participate in the Survey of Treatments Used by People with Multiple Sclerosis (Treat MS Survey), which is a survey that asks about the treatments you use to manage your MS and MS- related symptoms.
The survey, conducted by the Multiple Sclerosis Association of America (MSAA) and sponsored by Celgene, included more than 1, people with multiple sclerosis or someone responding on their behalf.
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This damage disrupts the ability of parts of the nervous system to communicate, resulting in a range of signs and symptoms, including physical, mental, and sometimes psychiatric problems.
A survey, summarizing the views of 2, multiple sclerosis (MS) patients, showed how people manage their disease in real life — and the results offer some surprising insights that might provide clues for future treatment development and optimization.
"Relapse Prevalence, Symptoms, and Health Care Engagement: Insights from Patients with Multiple Sclerosis from the Multiple Sclerosis in America Survey" [Poster P] includes data of 5, patients with MS on the prevalence and characterization of MS relapse and HCP engagement during and after relapse.
The annual survey was . Researchers at the University of Illinois College of Medicine are conducting a survey to evaluate Multiple Sclerosis Patient Needs and Satisfaction.
The questions focus on what you feel your healthcare team could improve upon/do differently to increase your satisfaction and see to all your needs.